Loganin alleviates testicular damage and germ cell apoptosis induced by AGEs upon diabetes mellitus by suppressing the RAGE/p38MAPK/NF‐κB pathway

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OBJECTIVES Rapamycin is an immunosuppressant compound with a broad spectrum of pharmaco-logical activities. In recent years, it has been used successfully to decrease ischemia-reperfusion injury in several organ systems. The purpose of the present study was to examine the effect of rapamycin on testicular ischemia-reperfusion injury. MATERIALS AND METHODS Seventy-two adult male Wistar rats we...

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ژورنال

عنوان ژورنال: Journal of Cellular and Molecular Medicine

سال: 2020

ISSN: 1582-1838,1582-4934

DOI: 10.1111/jcmm.15198